Devrais-je leur conseiller d’utiliser les plus anciens sédatifs?

J’ai entendu dire qu’ils étaient peut-être plus sécuritaires que les plus récentes classes de médicaments non sédatifs, à moins que les plus récents produits aient aussi fait l’objet d’études.

Conclusion Although seasonal allergy is not a life-threatening medical condition, it can be extremely troublesome for pregnant women and breast feeding mothers.

non sedating antihistamine comparison-38

View abstract Competing interests None declared Can Fam Physician Vol.

Research indicates that long-term use may not be the best solution By Alan L. Although etiology of these complaints was not obtained, we know that BPPV is the most common cause of vertigo, and disequilibrium and unsteadiness can be the result of vestibular and/or non-vestibular pathology.

RPONSE L’utilisation des antihistaminiques de la première génération est considérée sécuritaire pendant la grossesse.

Il y a relativement moins de données sur les antihistaminiques non sédatifs de la deuxième génération; par ailleurs, les études publiées sont rassurantes.

Although animal studies failed to show teratogenicity, decreases in pup weight and survival were observed.

There are no human data on fexofenadine Antihistamines and breastfeeding Although the data regarding the use of first-generation antihistamines and breastfeeding is limited, only minimal amounts of these drugs have been reported to be secreted in breast milk.Assuming the breast milk intake by an infant is 150 m L/kg daily, the maximum infant loratadine-equivalent dose based on the highest concentration of loratadine and desloratadine in breast milk was estimated to be 7.3 g/kg daily (ie, 1.1% of the daily dose given to the mother in mg/kg).The pharmacokinetics of fexofenadinein breast milk were studied in 4 lactating women taking 60 mgof terfenadine every 12 hours.ABSTRACT QUESTION Many of my pregnant and breastfeeding patients suffer from allergies and frequently ask me about the safety of antihistamines during pregnancy and breastfeeding.Should I advise them to use the older sedating medications?The maximum infant dose of fexofenadine based on the highest concentration of fexofenadinein breast milk would be 9 g/kg daily (ie, 0.45% of the daily dose given to the mother in mg/kg).