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This indicates the type of evidence that supports the existence of the protein.

Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed. This subsection of the ‘Function’ section specifies the position(s) of the calcium-binding region(s) within the protein.

of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced. This subsection of the Family and Domains section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold. This subsection of the Family and Domains section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold. This subsection of the Family and Domains section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold. This subsection of the Family and Domains section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold. This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples.

Additionally, this section gives relevant information on each alternative protein isoform. 10 20 30 40 50MADQLTDEQI SEFKEAFSLF DKDGDGCITT KELGTVMRSL GQNPTEAELQ 60 70 80 90 100DMINEVDADG NGTIDFPEFL NLMAKKMKDT DSEEELKEAF RVFDKDQNGF 110 120 130 140 ISAAELRHVM TNLGEKLTDE EVEEMIREAD VDGDGQINYE EFVKIMMAK The checksum is a form of redundancy check that is calculated from the sequence. It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.

One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist. This subsection of the ‘Function’ section specifies the position(s) of the calcium-binding region(s) within the protein.

One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist. This subsection of the ‘Names and taxonomy’ section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry.

Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’. This subsection of the ‘Names and taxonomy’ section contains the taxonomic hierarchical classification lineage of the source organism.

It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first. This subsection of the “Names and Taxonomy” section is present for entries that are part of a proteome, i.e. Cyclic redundancy and other checksums Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)) This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry.

The version number for both the entry and the canonical sequence are also displayed. This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by Uni Prot KB curators or not, in other words, if the entry belongs to the Swiss-Prot section of Uni Prot KB (reviewed) or to the computer-annotated Tr EMBL section (unreviewed).

Upon integration into Uni Prot KB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’. This subsection of the ‘Entry information’ section shows the date of integration of the entry into Uni Prot KB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’).

This subsection of the ‘Entry information’ section provides a mnemonic identifier for a Uni Prot KB entry, but it is not a stable identifier.